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Achieving Deeper Insight with a Consistent Analytical Data Structure

Achieving Deeper Insight with a Consistent Analytical Data Structure

Teams conducting biotherapeutic research use analytical data derived from molecular biology assays to assess the performance of protein targets. These often include simple measurements such as titer and amino acid measurements, as well as more complicated signal data assays like chromatography or differential scanning calorimetry. In order to effectively assess the performance of a protein target, analytical scientists must be able to compare results across multiple assays.

Consistent structure of analytical data is essential for conducting this type of cross experiment analysis. LabKey Biologics provides essential software tools to help protein engineering teams collect and centralize laboratory data with a structure that allows them to ask complex questions and achieve a deeper level of insight.

LabKey Biologics assay data templates ensure a consistent structure for analytical data.Configurable Assay Design Templates

Configurable assay design templates within LabKey Biologics provide a consistent structure for data being captured and ensure that each run of instrument data is stored in the same way. The use of a template for data capture prevents teams from accumulating data in independently designed spreadsheets when collected for different experiments or by different operators. Using an assay design template also allows you to indicate required fields, set data validation criteria, and normalize data as it is being brought into the central system.

Keep the same analytical data structure regardless of the upload method to import assay data.Easy Mechanisms for Importing Data

LabKey Biologics provides several straightforward methods for loading data into these consistent structures. These include:

  • Automated loading of data via LabKey Biologics API
  • Uploading data files (.xls, .csv., .tsv)
  • Copy/pasting tab separated values
  • Entering values directly into an assay grid

Importing data using any of these methods will populate the assay data structures discussed above, creating a structured catalog of analytical data for easy cross experiment analysis.

Using LabKey Biologics software tools to connect analytical data to sample details, cell culture media, and entity registration for protein therapeutic development.Powerful Querying of Sample Lineage

Consistently structured and centrally organized analytical data enables basic analysis and comparison of experiment results, but the real value of LabKey Biologics lies in the connection that the application makes between this data and the lineage of associated samples. Within LabKey Biologics users can view the lineage details of each sample; which bioreactor run a sample is derived from, what media recipe was used, or what molecule is was expressed. By connecting these details about a sample’s derivation and physical characteristics to structured data about it’s experimental performance, protein engineering teams can significantly reduce the amount of manual effort required to ask challenging questions of their data.

With the right tools, biologics R&D teams can significantly reduce time investment required to derive insight from their analytical data. Explore LabKey Biologics free for 30-days in our hosted trial environment, or contact us to request a demo.

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