World-renowned for its scientific discovery, the Icahn School of Medicine at Mount Sinai contains many research projects with varying objectives and would greatly benefit from a secure platform to share data across studies. Through a combination of multiple independent databases with a similar focus, the LabKey Server-based Inflammatory Bowel Disease (IBD) Integrated Database provides a clear overview of available research resources. IBD-centered studies at Mount Sinai have collected a plethora of data and samples from over 6,000 IBD-affected and non-affected study participants. Study contributions include large genotype datasets, questionnaire responses, clinical data, and a variety of samples, such as DNA, sera and tissue. In addition to providing a valuable resource for the Mount Sinai research community to make a major contribution in understanding IBD, the integrated database also guides new research projects through the supply of a framework, including data templates and dictionaries.