LabKey Server provides a comprehensive proteomics system for processing, analyzing, storing and sharing high volumes of tandem mass spectrometry data.
Sample Screens (click to enlarge)
The LabKey Server platform works exceptionally well for research teams
and organizations that need a system to process, analyze,
store and securely share high volumes of tandem mass spectrometry data.
LabKey Server incorporates a robust data pipeline for importing and processing MS/MS data from raw and mzXML data files. The pipeline manages the chain of processing steps needed to infer protein identifications and expression levels from the output of a mass spec machine. The pipeline integrates with leading search engines including X!TandemTM, MascotTM, and SequestTM. The pipeline also integrates PeptideProphetTM, ProteinProphetTM, and XPRESSTM, all components of the Trans Proteomic PipelineTM from the Institute for Systems Biology.
For analysis, LabKey Server displays the search results from one or many runs in your web browser, enabling you to filter, sort, customize, compare, and export experimental runs. You can share data securely with collaborators inside or outside your organization while exercising fine-grained control over permissions.
Today, LabKey Server powers proteomics repositories at the Fred
Hutchinson Cancer Research Center, Cedars-Sinai
Medical Center, the University of Washington and many others, where it
is central to efforts to identify predictive biomarkers for cancer.
LabKey's proteomics features, also known collectively as CPAS (for Computational Proteomics Analysis System) are caBIGTM compatible.
Proteomics Solution Components
Proteomics Core
LabKey Server easily manages tandem mass spectrometry analyses using a variety of popular search engines including MascotTM, SequestTM, and X-TandemTM.
Collaboration Tools
LabKey Server provides tools for sharing information and ideas on public and private webs. It includes a wiki for sharing dynamic content, a message board for online discussions and an issue tracker for workflow management.
Administration and Installation Tools
LabKey Server provides fine-grained control over project structures and user permissions. Administrators can add specialized tools to customized projects and folders.
Developers
The LabKey Software Foundation provides the LabKey Developer Community Forum for programmers who seek to customize or extend LabKey Server.
